研究成果

Original Paper 2020

Yamagaki, T., Yamazaki, T. “Practical Protocol for Making Calibration Curves for Direct and Sensitive Quantitative LC Orbitrap-MS of Large Neuropeptides.” Mass Spectrom., A0087 (2020). [Publisher] (open access)

Kabe, Y., Takemoto, D., Kanai, A., Hirai, M., Ono, Y., Akazawa, S., Horikawa, M., Kitagawa, Y., Handa, H., Rogi, T., Shibata, H., Suematsu, M. “Annexin A1 Accounts for an Anti-Inflammatory Binding Target of Sesamin Metabolites” NPJ Sci Food 4, 4 (2020). [Publisher] (open access)

Ono, E., Waki, T., Oikawa, D., Murata, J., Shiraishi, A., Toyonaga, H., Kato, M., Ogata, N., Takahashi, S., Yamaguchi, M. A., Horikawa, M., Nakayama, T. “Glycoside-specific glycosyltransferases catalyze regio-selective sequential glucosylations for a sesame lignan, sesaminol triglucoside” Plant J. 101, 1221-1233 (2020). [Publisher] (open access)

Matsubara S, Shiraishi A, Osugi T, Kawada T, Satake H. (2020) “Fractionation of Ovarian Follicles and in vitro Oocyte Maturation and Ovulation Assay of Ciona intestinalis Type A” Bio Protoc. 10(7), doi: 10.21769/BioProtoc.3577 [PubMed] open access

Osugi T, Sasakura Y, Satake H. (2020) “The ventral peptidergic system of the adult ascidian Ciona robusta (Ciona intestinalis Type A) Insights from a transgenic animal model” Sci Rep. 10(1), 1892, doi: 10.1038/s41598-020-58884-w [PubMed] open access.

Matsuo R, Kobayashi S, Furuta A, Osugi T, Takahashi T, Satake H, Matsuo Y. (2020) “Distribution and physiological effect of enterin neuropeptides in the olfactory centers of the terrestrial slug Limax” J Comp Physiol A 206(3), 401-418, doi: 10.1007/s00359-020-01400-2 [PubMed]

Mita M, Osugi T, Takahashi T, Watanabe T, Satake H. (2020) “Mechanism of gamete shedding in starfish: Involvement of acetylcholine in extracellular Ca²⁺-dependent contraction of gonadal walls” Gen Comp Endocrinol. 290, 113401, doi: 10.1016/j.ygcen.2020.113401. [PubMed]

Sugahara K*, Kitao K, Yamagaki T, Koyama T*. (2020) “Practical optimization of LC-MS conditions and pretreatment methods toward the sensitive quantification of auxin in plants”. Rapid Commun. Mass Spectrom. 34, e8625. [PubMed] (*, equal contributors.) open access

Morishita F, Takahashi T, Watanabe T, Uto T, Ukena K, Furumitsu M, Horiguchi T. (2020) “Identification of neuropeptides in gastropod mollusks. – Classical and brand-new approaches” – IOP Conf. Ser.: Earth and Environ. Sci. 456, 012001, doi: 10.1088/1755-1315/456/1/012001 open access

Tsugawa H, Kabe Y, Kanai A, Sugiura Y, Hida S, Taniguchi S, Takahashi T, Matsui H, Yasukawa Z, Itou H, Takubo K, Suzuki H, Honda K, Handa H, Suematsu M. (2020) Short-chain fatty acids bind to apoptosis-associated speck-like protein to activate inflammasomal complex to prevent Salmonella infection. PLoS Biol. 18(9), e3000813. [PubMed] open access

Takahashi T, Shiraishi A, Osawa M. Upregulated nicotinic ACh receptor signaling contributes to intestinal stem cell function through activation of Hippo and Notch signaling pathways. Int Immunopharmacol. 88, 106984. [PubMed]

Mita M, Matsubara S, Osugi T, Shiraishi A, Wada A, Satake H. (2020) “A novel G protein-coupled receptor for starfish gonadotropic hormone, relaxin-like gonad-stimulating peptide” PLoS One. 15(11), e0242877. doi: 10.1371/journal.pone.0242877. [PubMed]. open access.

Mayama S, Hamazaki N, Maruyama Y, Matsubara S, Kimura AP. (2020) “Transcriptional activation of the mouse Scd2 gene by interdependent enhancers and long noncoding RNAs in ovarian granulosa cells” J Reprod Dev. 66, 435-444. doi: 10.1262/jrd.2019-161. [PubMed] open access

Harada E*., Murata J*., Ono E*., Toyonaga H., Shiraishi A., Hideshima K., Yamamoto MP., Horikawa M. (+)-Sesamin-oxidizing CYP92B14 shapes specialized lignan metabolism in sesame. Plant J. 104, 1117-1128 (2020). (*, equal contributors), doi: 10.1111/tpj.14989 [PubMed] open access

Kikuchi A., Takayama H., Tsugane H., Shiba K., Chikamoto K., Yamamoto T., Matsugo S., Ishii K., Misu H., Takamura T. Plasma half-life and tissue distribution of leukocyte cell-derived chemotaxin 2
in mice. Sci Rep 10 (1), 1-11 (2020). [PubMed] open access

Original Paper 2019

Yamagaki, T., Yamazaki, T. “Troubleshooting carry-over in LC-MS analysis of biomolecules; The case of neuropeptide Y.” Mass Spectrom., S0083 (2019). [Publisher] (open access)

Sugahara, K., Kitao, K., Watanabe, T., Yamagaki, T. “Imaging mass spectrometry analysis of flavonoids in blue viola petals and their enclosure effects on violanin during color expression.” Analytical Chemistry. 91, 896-902 (2019). [Publisher] (open access)

Nomura, K., Yamaguchi, T., Mori, S., Fujikawa, K., Nishiyama, K., Shimanouchi, T., Tanimoto, Y., Morigaki, K., Shimamoto, K. “Alteration of membrane physicochemical properties by two factors for membrane protein integration” Biophys. J., 117, 99–110. (2019) [Publisher] (open access)

Tera, M., Luedtke, N. W. “Three-Component Bioorthogonal Reactions on Cellular DNA and RNA” Bioconjug. Chem., 30, 2991–2997. (2019) [Publisher]

Yamamoto, T., Yamagaki, T., Satake, H. “Development of software for deep analysis of protein dynamics as determined by MALDI mass spectrometry-based hydrogen/deuterium exchange.” Mass Spectrom., S0082 (2019). [Publisher] (open access)

Sawasato, K., Sato, R., Nishikawa, H., Iimura, N., Kamemoto, Y., Fujikawa, K.,Yamaguchi, T., Kuruma, Y., Tamura, Y., Endo, T., Ueda, T., Shimamoto, K., Nishiyama, K. “CdsA is involved in biosynthesis of glycolipid MPIase essential for membrane protein integration in vivo” Sci. Rep., 9, 1372 (2019) [Publisher] (open access)

Hoshino, A., Mizuno, T., Shimizu, K., Mori, S., Fukada-Tanaka, S., Furukawa, K., Ishiguro, K., Tanaka, Y., Iida, S. “Generation of yellow flowers of the Japanese morning glory by engineering its flavonoid biosynthetic pathway toward aurones.” Plant Cell Physiol. 60, 1871–1879 (2019). [Publisher] (open access)

Ishikawa, Y., Murai, Y., Sakata, M., Mori, S., Matsuo, S., Senuma, W., Ohnishi, K., Hikichi, Y., Kai, K. “Activation of ralfuranone/ralstonin production by plant sugars functions in the virulence of Ralstonia solanacearum.” ACS Chem. Biol. 14, 1546–1555 (2019). [Publisher]

Murakami, Y., Iwabuchi, H., Ohba, Y., Fukami, H. “Analysis of volatile compounds from Chili peppers and characterization of Habanero (Capsicum chinense) volatiles.” J. Oleo Sci. 68, 1251–1260 (2019). [PubMed] (open access)

Nomura, Y., Seki, H., Suzuki, T., Ohyama, K., Mizutani, M., Kaku, T., Tamura, K., Ono, E., Horikawa, M., Sudo, H., Hayashi, H., Saito, K., Muranaka, T. “Functional specialization of UDP-glycosyltransferase 73P12 in licorice to produce a sweet triterpenoid saponin, glycyrrhizin.” Plant J. 99, 1127-1143 (2019). [Publisher] (open access)

Ono E*, Waki T*, Oikawa D, Murata J, Shiraishi A, Toyonaga H, Kato M, Ogata N, Takahashi S,Yamaguchi MA, Horikawa M, Nakayama T. (2019) “Glycoside-specific glycosyltransferases catalyze regio-selective sequential glucosylations for a sesame lignan, sesaminol triglucoside.” Plant J. 101(5), 1221-1233. [PubMed] (*, equal contributors.) open access

Yamashiro T*, Shiraishi A*, Satake H, Nakayama K. (2019) “Draft genome of Tanacetum cinerariifolium, the natural source of mosquito coil.” Sci Rep. 9(1), 18249. [PubMed] (*, equal contributors.) open access

Matsubara S, Shiraishi A, Osugi T, Kawada T, Satake H. (2019) “The regulation of oocyte maturation and ovulation in the closest sister group of vertebrates.” eLife. 8, pii: e49062. [PubMed] open access

Aoyama M*, Shiraishi A*, Matsubara S, Horie K, Osugi T, Kawada T, Yasuda K, Satake H.(2019) “Identification of a New Theca/Interstitial Cell-Specific Gene and Its Biological Role in Growth of Mouse Ovarian Follicles at the Gonadotropin-Independent Stage.” Front Endocrinol (Lausanne). 10, 553. [PubMed] (*, equal contributors.) open access

Tera M*, Koyama T*, Murata J, Furukawa A, Mori S, Azuma T, Watanabe T, Hori K, Okazawa A,Kabe Y,Suematsu M, Satake H, Ono E, Horikawa M.(2019) “Identification of a binding protein for sesamin and characterization of its roles in plant growth.” Sci. Rep. 9(1), 8631. [PubMed] (*, equal contributors.) open access

Nagasawa K, Matsubara S, Satake H, Osada M. (2019) “Functional characterization of an invertebrate gonadotropin-releasing hormone receptor in the Yesso scallop Mizuhopecten yessoensis.” Gen. Comp. Endocrinol. 282, 113201. [PubMed]

Shiraishi A, Okuda T, Miyasaka N, Osugi T, Okuno Y, Inoue J, Satake H. (2019) “Repertoires of G protein-coupled receptors for Ciona-specific neuropeptides.” Proc. Natl. Acad. Sci. U S A. 116(16), 7847-7856. [PubMed] open access

Original Paper 2018

Fujikawa, K., Suzuki, S., Nagase, R., Ikeda, S., Mori, S., Nomura, K., Nishiyama,K., Shimamoto, K., “Syntheses and activities of the functional structures of a glycolipid essential for membrane protein integration” ACS Chem. Biol., 13, 2719–2727 (2018) [Publisher] (open access)

Mori, S., Sugahara, K., Maeda, M., Shimamoto, K., Iwashita, T., Yamagaki, T. “Truncated palytoxin analogue, palytoxin carboxylic acid, isolated as an insecticidal compound from the red alga, Chondria armata.” Tetrahedron Lett. 59, 4420–4425 (2018). [Publisher] (open access)

Tera, M., Harati Taji, Z., Luedtke, N. W. “Intercalation-enhanced “Click” Crosslinking of DNA.” Angew. Chem. Int. Ed. 57, 15405–15409 (2018). [Publisher]

Tera, M., Glasauer, S., Luedtke, N. W. “Incorporation of azide groups into DNA using membrane-permeable nucleotide triesters in vivo.” ChemBioChem 19, 1939–1943 (2018). [Publisher]

Murakami, Y., Iwabuchi, H., Horikawa, M., Mori, S., Ohba, Y., Fukami, H. “Isolation and identification of a volatile compound in Habanero pepper (Capsicum chinense).” J. Oleo Sci. 67, 1219-1225 (2018). [PubMed] (open access)

Morishima, K., Nakamura, N., Matsui, K., Tanaka, Y., Masunaga, H.,Mori, S.,Iwashita, T., Li, X., Shibayama, M. “Formation of clusters in whiskies during the maturation process.” J. Food Sci. 84, 59–64 (2019). [Publisher] (open access)

Ono, E., Murata, J., Toyonaga, H., Nakayasu, M., Mizutani, M., Yamamoto, M. P., Umezawa, T., Horikawa, M. “Formation of a methylenedioxy bridge in (+)-epipinoresinol by CYP81Q3 corroborates with diastereomeric specialization in sesame lignans.” Plant Cell Physiol. 59, 2278-2287 (2018). [Publisher] (open access)

Okitsu, N., Matsui, K., Horikawa, M., Sugahara, K., Tanaka, Y. “Identification and characterization of novel Nemophila menziesii flavone glucosyltransferases that catalyze biosynthesis of flavone 7,4′-O-diglucoside, a key component of blue metalloanthocyanins.” Plant Cell Physiol. 59, 2075-2085 (2018). [Publisher] (open access)

Satoh T, Iitsuka T, Shiraishi A, Hozumi A, Satake H, Sasakura Y. (2018) “piRNA-like small RNAs are responsible for the maternal-specific knockdown in the ascidian Ciona intestinalis Type A.” Sci Rep. 8(1), 5869. [PubMed] open access

Takahashi T, Shiraishi A, Murata J. (2018) The coordinated activities of nAChR and Wnt signaling regulate intestinal stem cell function in mice. Int. J. Mol. Sci. 19, E738. [PubMed] open access

Koyama T, Sato F. (2018) “The function of ETHYLENE RESPONSE FACTOR genes in the light-induced anthocyanin production of Arabidopsis thaliana leaves”. Plant Biotechnol. 35, 87-92. [PubMed] open access

Original Paper 2017

Yamagaki,T., Makino, Y. “Fragmentation of oligosaccharides from sodium adduct molecules depends on the position of N-acetyl hexosamine residue in their sequences in mass spectrometry.” Mass Spectrom. (Tokyo), 6, S0073 (2017). [PubMed] (open access)

Nomura, K., Tanimoto, Y., Hayashi, F., Harada, E., Shan, X. Y., Shionyu, M., Hijikata, A., Shirai, T., Morigaki, K., Shimamoto, K. “The role of the prod1 membrane anchor in newt limb regeneration.” Angew Chem Int Ed Engl. 56, 270-274 (2017). [PubMed] (open access)

Nakamura M., Makino Y., Takagi C., Yamagaki T, Sato M., “Probing the catalytic site of rabbit muscle glycogen phosphorylase using a series of specifically modified maltohexaose derivatives.” Glycoconj J. 34, 563-574 (2017).

Hayashi, T., Osawa, A., Watanabe, T., Murata, Y., Nakayama, A., Namba K., “Development of 1,3a,6a-triazapentalene-labeled enterobactin as a fluorescence quenching sensor of iron ion” Tetrahedron Letters, 58, 1961-1964 (2017). [publisher]

Suno, R., Kimura, K.T., Nakane, T., Yamashita, K., Wang, J., Fujiwara, T., Yamanaka, Y., Im, D., Horita, S., Tsujimoto, H., Tawaramoto, M.S., Hirokawa, T., Nango, E., Tono, K., Kameshima, T., Hatsui, T., Joti, Y., Yabashi, M., Shimamoto,K., Yamamoto, M., Rosenbaum, D.M., Iwata, S., Shimamura, T., Kobayashi, T. “Crystal structures of human orexin 2 receptor bound to the subtype-selective antagonist EMPA.” Structure, 26, 7-19 (2017). [PubMed]

Murai, Y., Mori, S., Konno, H., Hikichi, Y., Kai, K. “Ralstonins A and B, lipopeptides with chlamydospore-inducing and phytotoxic activities from the plant pathogen Ralstonia solanacearum” Org. Lett., 19, 4175-4178 (2017). [publisher]

Satake, M., Cornelio, K, Hanashima, S., Malabed, R., Murata, M., Matsumori, N., Zhang, H., Hayashi, H., Mori, S., Kim, J. S., Kim, C.-H., Lee, J.-S. “Structures of the largest amphidinol homologues from the dinoflagellate Amphidinium carterae and structure−activity relationships” J. Nat. Prod., 80, 2883-2888 (2017). [publishe r]

Fujimaki, T., Mori, S., Horikawa, M., Fukui, Y. “Isolation of proanthocyanidins from red wine, and their inhibitory effects on melanin synthesis in vitro” Food Chem., 248, 61-69 (2017). [publisher]

Murata J*, Ono E*, Yoroizuka S*, Toyonaga H, Shiraishi A, Mori S, Tera M, Azuma T, Nagano AJ, Nakayasu M, Mizutani M, Wakasugi T, Yamamoto MP, Horikawa M. (2017) “Oxidative rearrangement of (+)-sesamin by CYP92B14 co-generates twin dietary lignans in sesame.” Nat. Commun. 8, 2155. [PubMed] (* , equal contributors.) open access

Kurihara M, Otsuka K, Matsubara S, Shiraishi A, Satake H, Kimura AP. (2017) “A Testis-Specific Long Non-Coding RNA, lncRNA-Tcam1, Regulates Immune-Related Genes in Mouse Male Germ Cells.” Front Endocrinol. 8, 299. [PubMed] open access

Matsubara S, Shiraishi A, Sakai T, Okuda T, Satake H. (2017) “Heterodimerization of the prostaglandin E2 receptor EP2 and the calcitonin receptor CTR.” PLOS One. 12(11), e0187711. [PubMed] open access

Osugi T, Sasakura Y, Satake H. (2017) “The nervous system of the adult ascidian Ciona intestinalis Type A (Ciona robusta): Insights from transgenic animal models.” PLOS One. 12(6), e0180227. [PubMed]. open access

Kase Y, Ikari T, Sekiguchi T, Sato M, Ogiso S, Kawada T, Matsubara S, Satake H, Sasayama Y, Endo M, Kitamura KI, Hattori A, Watanabe TX, Maruyama Y, Watanabe Y, Funahashi H, Kambegawa A, Suzuki N. (2017) “Sardine procalcitonin amino-terminal cleavage peptide has a different action from calcitonin and promotes osteoblastic activity in the scales of goldfish.” Comp. Biochem. Physiol. A Mol. Integr. Physiol. 211, 77-83. [PubMed]

Kawada T, Shiraishi A, Aoyama M Satake H. (2017). “Transcriptomes of the premature and mature ovaries of an ascidian, Ciona intestinalis.” Front. Endocrinol. 8, 88. [PubMed] open access

Sekiguchi T,Shiraishi A, Satake H, Kuwasako K, Takahashi H, Sato M, Urata M, Wada S, Endo M, Ikari T, Hattori A, Srivastav AK, Suzuki N. (2017) “Calcitonin-typical suppression of osteoclastic activity by amphioxus calcitonin superfamily peptides and insights into the evolutionary conservation and diversity of their structures.” Gen. Comp. Endocrinol. 246, 294-300. [PubMed]

Takahashi T. (2017) Visualization of acetylcholine distribution in intestinal tissue sections by tandem imaging mass spectrometry and its function in mice. J. Neurochem. 142 (Suppl. 2), 203-204. [PubMed]

Koyama T, Sato F, Ohme-Takagi M. (2017) “Roles of miR319 and TCP transcription factors in leaf development”. Plant Physiol. 175, 874-885. [PubMed] open access

Kubota A, Ito S, Shim JS, Johnson R, Y Song Y, Breton G, Golembeski G, Kwon M, Laboy D,Koyama T, Ohme-Takagi M, Pruneda-Paz J, Kay S, MacCoss MJ, Imaizumi T. (2017) “TCP4-dependent Induction of CONSTANS Transcription Requires GIGANTEA in Photoperiodic Flowering in Arabidopsis”. PLOS Genet. 13, e1006856. [PubMed] open access

Original Paper 2016

Yamagaki, T., Takeuchi, M., Watanabe, T., Sugahara, K., Takeuchi, T., Mechanism for odd-electron anion generation of dihydroxybenzoic acid isomers in matrix-assisted laser desorption/ionization mass spectrometry with density functional theory calculations. Rapid Commun. Mass Spectrom., 24, 2650-2654 (2016) [Publisher] (open access)

Mori S., Sugahara K., Maeda M., Nomoto K., Iwashita T., Yamagaki T., “Insecticidal activity guided isolation of palytoxin from a red alga, Chondria armata.” Tetrahedron Lett. 57, 3612-3617 (2016). [publisher] (open access)

Sugahara K., Horikawa M., Yamagaki T, “Amino-β-cyclodextrin complex assisted ionization for labile sesamins and their ionmobility separation in ESI Q-TOF MS.” Mass Spectrom. Lett. 6, 17-20 (2016) [Publisher] (open access)

Iwashita, T., Konuma, T., Harada, E., Mori, S., Sugase, K. “Use of glass capillaries to suppress thermal convection in NMR tubes in diffusion measurements.” Magn. Reson. Chem., 54, 729–733 (2016). [publisher]

Yasuno, Y., Hamada, M., Yoshida, K., Shimamoto, K., Shigei, Y., Akizawa, T., Konishi, M., Ohfune, Y., Shinada, T. “Structure-activity relationship study at C9 position of kaitocephalin.” Bioorg. Med.
Chem. Lett. 26, 3543-3546 (2016). [publisher]

Yasuno, Y., Hamada, M., Kawasaki, M., Shimamoto, K., Shigei, Y., Akizawa, T., Konishi, M., Ohfune, Y., Shinada, T. “(7S)-Kaitocephalin as a potent NMDA receptor selective ligand.” Org. Biomol. Chem., 14, 1206-1210. (2016). [publisher]

Kabe, Y., Nakane, T., Koike, I.,Yamamoto, T., Sugiura, Y., Harada, E., Sugase, K.,Shimamura, T., Ohmura, M., Muraoka, K., Yamamoto, A., Uchida, T., Iwata, S.,Yamaguchi, Y., Krayukhina, E., Noda, M., Handa, H., Ishimori, K., Uchiyama, S., Kobayashi, T., Suematsu, M. “Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance.” Nat. Commun. 7, 11030 (2016). [PMC Free full text] doi: 10.1038/ncomms11030

Shiraishi A*, Murata J*, Matsumoto E, Matsubara S, Ono E, Satake H. (2016) “De novo transcriptomes of Forsythia koreana using a novel assembly method: insight into tissue- and species-specific expression of lignan biosynthesis-related gene. PLOS One. 11, e0164805. [PubMed] (*, equal contributors) open access

Sekiguchi T, Kuwasako K, Ogasawara M, Takahashi H, Matsubara S, Osugi T, Muramatsu I,Sasayama Y, Suzuki N, Satake H. (2016) “Evidence for conservation of the calcitonin superfamily and activity-regulating mechanisms in the basal chordate Branchiostoma floridae: insight into the molecular and functional evolution in chordates.” J. Biol. Chem. 291, 2345-2356. [PubMed] open access

Ono E, Handa T, Koeduka T, Toyonaga H, Tawfik MM, Shiraishi A, Murata J, Matsui K. (2016). CYP74B24 is the 13-hydroperoxide lyase involved in biosynthesis of green leaf volatiles in tea (Camellia sinensis). Plant Physiol. Biochem. 98, 112-118. [PubMed]

Ainsworth EV, Lockwood CW, White GF, Hwang ET, Sakai T, Gross MA, Richardson DJ, Clarke TA, Jeuken LJ, Reisner E, Butt JN. (2016) “Photoreduction of Shewanella oneidensis Extracellular Cytochromes by Organic Chromophores and Dye-Sensitized TiO(2).” Chembiochem. 17:2324-2333.
doi: 10.1002/cbic.201600339. [PubMed]

Harada E, Sugase K, Namba K, Murata Y. (2016) “The helical propensity of the extracellular loop is responsible for the substrate specificity of Fe(III)-phytosiderophore transporters” FEBS Lett. 590, 4617-4627. [PubMed] open access

Original Paper 2015

Tera M., Hirokawa T., Okabe S., Sugahara K., Seimiya H., Shimamoto K., “Design and synthesis of a berberine dimer: A fluorescent ligand with high affinity towards G-quadruplexes” Chem. Eur. J., 21, 14519-14528 (2015). [Publisher]

Harada, E., Sugishima, M., Harada, J., Noguchi, M., Fukuyama, K., Sugase, K. “Backbone assignments of the apo and Zn(II) protoporphyrin IX-bound states of the soluble form of rat heme oxygenase-1.” Biomol. NMR Assign. 9, 197-200 (2015). [PubMed]

Harada, E., Sugishima., M., Harada., J., Fukuyama, K., Sugase, K. “Distal regulation of heme binding of heme oxygenase-1 mediated by conformational fluctuations.” Biochemistry 54, 340-348 (2015). [PubMed]

Ohgami, S., Ono, E., Horikawa, M., Murata, J., Totsuka, K., Toyonaga, H., Ohba, Y., Dohra, H., Asai, T., Matsui, K., Mizutani, M., Watanabe, N., Ohnishi, T. “Volatile glycosylation in tea plants: Sequential glycosylations for the biosynthesis of aroma β-primeverosides are catalyzed by two Camellia sinensis glycosyltransferases” Plant Physiology, 168, 464-477 (2015).[Free full text]

Konuma, T., Harada, E., Sugase, K. “Extracting protein dynamics information from overlapped NMR signals using relaxation dispersion difference NMR spectroscopy.” J. Biomol. NMR. 63, 367-373 (2015). [PubMed]

Murata J, Matsumoto E, Morimoto K, Koyama T, Satake H. (2015) “Generation of triple-transgenic Forsythia cell cultures as a platform for the efficient, stable, and sustainable production of lignans.” PLOS One. 10, e0144519. [PubMed] open access

Nagasawa, K.,* Osugi, T.,* Suzuki, I., Itoh, N., Takahashi, K.G., Satake, H., Osada, M. (2015) “Characterization of GnRH-like peptides from the nerve ganglia of Yesso scallop, Patinopecten yessoensis.” Peptides 71, 202-210. [PubMed] (*, equal contributors) open access

Natsume, S., Takagi, H., Shiraishi, A., Murata, J., Toyonaga, H., Patzak, J., Takagi, M., Yaegashi, H., Uemura, A., Mitsuoka, C., Yoshida, K., Krofta, K., Satake, H., Terauchi, R., Ono, E. (2015) “The draft genome of hop (Humulus lupulus), an essence for brewing.” Plant Cell Physiol. 56, 428-441. [PubMed] open access

Araki R, Kousaka K, Namba K, Murata Y, Murata J. (2015) 2’-Deoxymugineic acid promotes growth of rice (Oryza sativa L.) by orchestrating iron and nitrate uptake processes under high pH conditions. Plant J. 81, 233-246. [PubMed] open access

Murata J, Watanabe T, Sugahara K, Yamagaki T, Takahashi T. (2015) High-resolution mass spectrometry for detecting Acetylcholine in Arabidopsis. Plant Signal. Behav. 10, e1074367. [PubMed] open access

Murata Y, Itoh Y, Iwashita T, Namba K. (2015) “Transgenic petunia with the iron(III)-phytosiderophore transporter gene acquires tolerance to iron deficiency in alkaline environments.” PLOS One. 10, e0120227. [PubMed] open access

Original Paper 2014

Yamagaki, T., Watanabe, T., Tanaka, M., Sugahara, K., “Laser-induced hydrogen radical removal in MALDI-MS allows for the differentiation of flavonoid monoglycoside isomers” J. Am. Soc. Mass Spectrom., 25, 88-94 (2014). [PMC Free full text]

Yamagaki, T., Sugahara, K., Watanabe, T., “Amino and acetamide functional group effects on the ionization and fragmentation of sugar chains in positive-ion mass spectrometry.” J. Am. Soc. Mass Spectrom., 25, 95-103 (2014) [Publisher][PMC Free full text] (open access)

Nomura, K., Harada, E., Sugase, K., Shimamoto, K. “Solid-state NMR spectra of lipid-anchored proteins under magic angle spinning.” J. Phys.Chem. B. 118, 2405-2413 (2014). [PubMed]

Noguchi, A., Horikawa, M., Murata, J., Tera, M., Kawai, Y., Ishiguro, M., Umezawa, T., Mizutani, M., Ono, E. “Mode-of-action and evolution of methylenedioxy bridge forming P450s in plant specialized metabolism” Plant Biotechnology 31, 493-503 (2014). [Free full text]

Martinov, V., Dehnes, Y., Holmseth, S., Shimamoto, K., Danbolt, N. C., Valen, G. “A novel glutamate transporter blocker, LL-TBOA, attenuates ischaemic injury in the isolated, perfused rat heart despite low transporter levels.” Eur. J. Cardiothorac. Surg. 45, 710-716 (2014). [PubMed]

Sasaki, S., Suzuki, H., Ouchi, H., Asakawa, T., Inai, M., Sakai, R., Shimamoto, K., Hamashima, Y., Kan, T. “Practical synthesis of kainoids: a new chemical probe precursor and a fluorescent probe.” Org Lett. 16, 564-567 (2014). [PubMed]

Okazawa, A., Kusunose, T., Ono, E., Kim, H.-J., Satake, H., Shimizu, B., Mizutani, M., Seki, H., Muranaka, T. (2014) “Glucosyltransferase activity of Arabidopsis UGT71C1 towards pinoresinol and lariciresinol.” Plant Biotechnol. 31, 561-566. [J-Stage] open access

Bahabadi, S.E., Sharifi, M., Chashmi, N.A. Murata, J.,Satake, H. (2014) “Significant enhancement of lignans accumulation in hairy root cultures of Linum album using biotic elicitors” Acta Physiol. Plant. 36, 3325–3331 [Publisher]

Kamiya, C., Ohta, N., Ogura, Y., Yoshida, K., Horie, T., Kusakabe, T.G., Satake, H., Sasakura, Y. (2014) “Nonreproductive role of gonadotropin-releasing hormone in the control of ascidian metamorphosis.” Dev. Dyn. 243, 1524-1535. [PubMed] open access

Kurihara, M., Shiraishi, A., Satake, H., Kimura A.P. (2014) “A conserved noncoding sequence can function as a spermatocyte-specific enhancer and a bidirectional promoter for a ubiquitously expressed gene and a testis-specific long noncoding RNA.” J. Mol. Biol. 426, 3069-3093. [PubMed]

Bahabadi, S.E., Sharifi, M., Murata, J., Satake, H. (2014) “The Effect of Chitosan and Chitin Oligomers on Gene Expression and Lignan Production in Linum album Cell Cultures.” J. Med. Plant. 13, 46-53. [Publisher]

Noguchi A, Horikawa M, Murata J, Tera M, Kawai Y, Ishiguro M, Umezawa T, Mizutani M, Ono E. (2014) Mode-of-action and evolution of methylenedioxy bridge forming cytochrome P450s in plant specialized metabolism. Plant Biotechnol. 31, 1-11. [Publisher] open access

Takahashi, T., Ohnishi, H., Sugiura, Y., Honda, K., Suematsu, M., Kawasaki, T., Deguchi, T., Orihashi, K., Hippo, Y., Watanabe, T., Yamagaki, T., Yuba, S. (2014) “Non-neuronal acetylcholine as an endogenous regulator of proliferation and differentiation of Lgr5-positive stem cells in mice.” FEBS J. 281, 4672-4690. [PubMed] open access

Original Paper 2013

Nagata, A., Hamamoto, A., Horikawa, M., Yoshimura, K., Takeda, S., Saito, Y. “Characterization of ciliary targeting sequence of rat melanin-concentrating hormone receptor 1.” Gen. Comp. Endocrinol. 188, 159-165 (2013). [PubMed]

Mizohata, E., Okuda, T., Hatanaka, S., Nakayama, T., Horikawa, M., Nakayama, T., Ono, E., Inoue, T. “Crystallization and preliminary X-ray crystallographic analysis of UDP-glucuronic acid:flavonol-3-O glucuronosyltransferase (VvGT5) from the grapevine Vitis vinifera.” Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 69, 65-68 (2013). [PubMed] [PMC Free full text]

Iida K., Yoshida W., Nakamura T., Tera M., Nakabayashi K., Hata K., Ikebukuro K., Nagasawa K., “Fluorescent ligand-mediated screening of G-quadruplex structure using a DNA microarray” Angew. Chem. Int. Ed., 52, 12052-12055 (2013). [Publisher]

Chung W. J., Heddi B., Tera M., Iida K., Nagasawa K., Phan A. T., “Solution structure of an intramolecular (3 + 1) human telomeric G-quadruplex bound to a telomestatin derivative” J. Am. Chem. Soc., 135, 13495-13501 (2013). [Publisher]

Raj, H., Szymanski, W., de Villiers, J., Puthan Veetil, V., Quax, W. J., Shimamoto,K., Janssen D. B., Feringa, B. L., Poelarends, G. J. “Kinetic resolution and stereoselective synthesis of 3-substituted aspartic acids by using engineered methylaspartate ammonia lyases.” Chemistry, 19, 11148-11152 (2013). [PubMed]

Morimoto, K., Satake, H. (2013) “Seasonal alteration in amounts of lignans and their glucosides and gene expression of the relevant biosynthetic enzymes in the Forsythia suspense leaf.” Biol. Pharm. Bull. 36, 1519-1523. [PubMed] open access

Hata, N., Hayashi, Y., Ono, E., Satake, H., Kobayashi, A., Muranaka, T., Okazawa, A. (2013) “Differences in plant growth and leaf sesamin content of the lignan-rich sesame variety ‘Gomazou’ under continuous light of different wavelengths.” Plant Biotechnol. 30, 1-8. [J-Stage] open access

Hozumi, A., Mita, K., Hackett, P, Miskey, C., Mates, L., Izsvak, Z., Ivics, Z., Satake, H., Sasakura, Y. (2013) “Germline transgenesis of the chordate Ciona intestinalis with hyperactive variants of sleeping beauty transposable element.” Dev. Dyn. 242, 30-43. [PubMed] open access

Matsui, T., Sakai, T., Satake, H., Takeda M. (2013) “The pars intercerebralis affects digestive activities of the American cockroach, Periplaneta Americana, via crustacean cardioactive peptide and allatostatin-A.” J. Insect Physiol. 59, 33-37. [PubMed]

Takaku, Y., Shimizu, H., Takahashi, T., Fujisawa, T. (2013) “Subcellular localization of the epitheliopeptide, Hym-301 in hydra.” Cell Tissue Res. 351, 419-424. [PubMed]

Takeda, N., Nakajima, Y., Koizumi, O., Fujisawa, T., Takahashi, T., Matsumoto, M., Deguchi, R. (2013). “Neuropeptides trigger oocyte maturation and subsequent spawning in the hydrozoan jellyfish Cytaeis uchidae.” Mol. Reprod. Dev. 80, 223-232. [PubMed] open access

Sakai T, Mersch D, Reisner E. (2013) “Photocatalytic hydrogen evolution with a hydrogenase in a mediator-free system under high levels of oxygen.” Angew Chem Int Ed Engl. 252, 12313-12316. [PubMed] open access

Original Paper 2012

Nishiyama, K., Maeda, M., Nagase, R., Yanagisawa, K., Komura, H., Iwashita, T., Yamagaki, T., Kusumoto, S., Tokuda, H., Shimamoto, K. (2012) “MPIase is a glycolipozyme essential for membrane protein integration.” Nature Commun. 3, DOI: 10.1038/ncomms2267. [PubMed]

Yamagaki, T., Watanabe, T.. “Hydrogen radical removal causes complex overlapping isotope patterns of aromatic carboxylic acids in negative-ion matrix-assisted laser desorption/ionization mass spectrometry” Mass Spectrom., 1, A0005 (2012) [Publisher] (Open access)

Yoshinaka-Niitsu A., Yamagaki T., Harada M., Tachibana K.. “Solution NMR analysis of the binding mechanism of DIVS6 model peptides of voltagegated sodium channels and the lipid soluble alkaloid veratridine.” Bioorg. Med. Chem., 20, 2796-2802 (2012). [Publisher]

Sayama, T., Ono, E., Takagi, K., Takada, Y., Horikawa, M., Nakamoto, Y., Hirose, A., Sasama, H., Ohashi, M., Hasegawa, H., Terakawa, T., Kikuchi, A., Kato, S., Tatsuzaki, N., Tsukamoto, C., Ishimoto, M. “The Sg-1 glycosyltransferase locus regulates structural diversity of triterpenoid saponins of soybean.” Plant Cell. 24, 2123-2138 (2012). [Publisher] (open access)

Minagawa, S., Inami, H., Kato, T., Sawada, S., Yasuki, T., Miyairi, S., Horikawa,M., Okuda, J., Gotoh, N. “RND type efflux pump system MexAB-OprM of pseudomonas aeruginosa selects bacterial languages, 3-oxo acyl-homoserine lactones, for cell-to-cell communication.” BMC Microbiol.12, 70 (2012), DOI: 10.1186/1471-2180-12-70. [Publisher] (open access)

Hamamoto, A., Horikawa, M., Saho, T., Saito, Y. “ Mutation of Phe318 within the NPxxY(x)(5,6)F motif in melanin-concentrating hormone receptor 1 results in an efficient signaling activity. Front. Endocrinol. (Lausanne). 26, 147 (2012). [Publisher] (open access)

Kusakabe, T.G., Sakai, T., Aoyama, M., Kitajima, Y., Miyamoto, Y., Takigawa, T., Daido, Y., Fujiwara, K., Terashima, Y., Sugiuchi, Y., Matassi, G., Yagisawa, H., Park, M.-K., Satake, H., Tsuda M. (2012) “A conserved non-reproductive GnRH system in chordates.” PLoS One 7, e41955. [PubMed] open access

Deguchi, T., Kawasaki, T., Ohnishi, H., Yuba, S., Takahashi T. (2012) “Identification and developmental expression of leucine-rich repeat-containing G protein-coupled receptor 6 (lgr6) in the medaka fish, Oryzias Latipes.” Dev. Genes Evol. 222, 217-227. [PubMed] open access

Suzuki, N., Sekiguchi, T., Satake, H., Kato, K., Nishiyama, Y., Takahashi, H., Danks, J.A.., Martin, J., Hattori, A.., Nakano, M., Kakikawa, M., Yamada, S., Ogoshi, M., Hyodo, S., Yamaguchi, Y., Chowdhury, V.S., Hayakawa, K., Funahashi, H., Sakamoto, T., Sasayama, Y. (2012) “Cloning of two members of the calcitonin-family receptors from stingray, Dasyatis akajei: Possible physiological roles of the calcitonin family in osmoregulation” Gene. 499, 326-331. [PubMed]

Sekiguchi, T., Ogasawara, M., Satake, H. (2012) Molecular and functional characterization of cionin receptors in the ascidian, Ciona intestinalis: the evolutionary origin of the vertebrate cholecystokinin/gastrin family.” J. Endocrinol. 213, 99-106. [PubMed]

Sakai, T., Aoyama, M., Kawada, T., Kusakabe, T., Tsuda, M., Satake, H. (2012) “Evidence for differential regulation of GnRH signaling via heterodimerization among GnRH receptor paralogs in the protochordate, Ciona intestinalis.” Endocrinology. 153, 1841-1849. [PubMed] open access

Aoyama, M., Kawada, T., Satake, H. (2012) “Localization and enzymatic activity profiles of the proteases responsible for tachykinin-directed oocyte growth in the protochordate, Ciona intestinalis.” Peptides. 34, 186-192. [PubMed]

Bahabadi, S.E., Sharifi, M., Behmanesh, M., Safaie, N., Murata, J., Araki, R., Yamagaki, T., Satake,H. (2012) Time-course changes in fungal elicitor-induced lignan synthesis and expression of the relevant genes in cell cultures of Linum album. J. Plant Physiol. 169, 487-491. [PubMed]

Hata, N., Hayashi, Y., Okazawa, A., Ono, E., Satake, H., Kobayash, A. (2012) “Effect of photoperiod on growth of the plants, and sesamin content and CYP81Q1 gene expression in the leaves of sesame (Sesamum indicum L.).” Envir. Exp. Bot. 75, 212-219. [Publisher]

Original Paper 2011

Nomura, K., Lintuluoto, M., Morigaki, K., “Hydration and temperature dependence of 13C and 1H NMR spectra of the DMPC phospholipid membrane and complete resonance assignment of its crystalline state.” J. Phys.Chem. B. 115, 14991-15001 (2011). [PubMed]

Nomura, K., Maeda, M., Sugase, K., Kusumoto, S. “Lipopolysaccharide induces raft domain expansion in membrane composed of a phospholipid-cholesterol-sphingomyelin ternary system.” Innate Immun. 17, 256-268 (2011). [PubMed] (open access)

Matsumori, N., Okazaki, H., Nomura, K., Murata, M., “Fluorinated cholesterol retains domain-forming activity in sphingomyelin bilayers.” Chem. Phys. Lipids. 164, 401-408 (2011). [PubMed]

Bahabadi, S.E., Sharifi, M., Safaie, N., Murata, J., Yamagaki, T., Satake, H. (2011) “Increased lignan biosynthesis in the suspension cultures of Linum album by fungal extracts.” Plant Biotechnol. Rep. 5, 367-373. [Publisher]

Morimoto, K., Kim H.-J., Ono, E., Kobayashi, A., Okazawa, A., Satake, H. (2011) “Effects of light on production of endogenous and exogenous lignans by Forsythia koreana wildtype and transgenic cells.” Plant Biotechnol. 28, 331-337. [J-STAGE] open access

Kawada, T., Ogasawara, M., Sekiguchi, T., Aoyama, M., Hotta, K., Oka, K, Satake, H. (2011) “Peptidomic analysis of the central nervous system of the protochordate, Ciona intestinalis: homologs and prototypes of vertebrate peptides and novel peptides.” Endocrinology. 152, 2416-2427. [PubMed] open access

Okazawa, A., Hori, K., Okumura, R., Izumi, Y., Hata, N., Bamba, T., Fukusaki, E., Ono, E., Satake,H., Kobayashi, A. (2011) “Simultaneous quantification of lignans in Arabidopsis thaliana by highly sensitive capillary liquid chromatography-electrospray ionization-ion trap mass spectrometry.” Plant Biotechnol. 28, 287-293. [J-STAGE] open access

Morimoto, K., Ono, E., Kim, H.-J., Okazawa, A., Kobayashi, A., Satake, H. (2011) “The construction of transgenic Forsythia plants: comparative study of three Forsythia species” Plant Biotechnol. 28, 273-280. [J-STAGE] open access

Hamada, M., Shimozono, N., Ohta, N., Satou, Y., Horie, T., Kawada, T., Satake, H., Sasakura, Y., Satoh, N. (2011) “Expression of neuropeptide- and hormone-encoding genes in the Ciona intestinalis larval brain.” Dev. Biol. 352, 202-214. [PubMed] open access

Yamanaka, N., Roller, L., Žitňan, D., Satake, H., Mizoguchi, A., Kataoka, H., Tanaka, Y. (2011) “Bombyx orcokinins are brain-gut peptides involved in the neuronal regulation of ecdysteroidogenesis.” J. Comp. Neurol. 519, 238-246. [PubMed]

Rodríguez, A., Villegas, E., Satake, H., Possani, L.D., Corzo, G. (2011) “Amino acid substitutions in an alpha-helical antimicrobial arachnid peptide affect its chemical properties and biological activity towards pathogenic bacteria but improves its therapeutic index.” Amino Acids 40, 61-68. [PubMed]

Araki, R., Murata, J., Murata, Y. (2011) “A novel barley yellow stripe 1-like transporter (HvYSL2) localized to the root endodermis transports metal–phytosiderophore complexes.” Plant Cell Physiol. 52, 1931-1940. [PubMed] open access

Zenkert, C., Takahashi, T., Diesner, M-O., Ozbek, S. (2011) “Morphological and molecular analysis of the Nematostella vectensis Cnidom.” PLoS ONE 6, e22725. [PubMed] open access